In my opinion both cartridges require good shot placement. You'll find that to be the case with most anything you shoot. I've lost coyotes with both the .223 and the 22-250 due to poor shot placement. A coyote hit in the guts can run a long, long ways before piling up. One thing I've noticed between the two cartridges is if you hit them in the right spot they fall down and die. As you'll find with any cartridge you choose. So basically what I'm saying is every coyote I've hit in the vitals from 300 yards or closer with the .223 wasn't any less dead than any coyote I've ever shot from the same distance with the 22-250. And the ones I lost after shooting them in the guts with the 22-250 weren't any easier to find than the ones I lost using the .223, they both ran the same distance after being shot as far as I'm concerned. Can't confirm that because I never found either. You can probably get where I'm going with this.
The 22-250 really shines when you're shooting coyotes at 300+ yards. And even at 300 yards I don't feel under gunned with the .223 by any means. If you hit coyotes in the head, neck, lungs or heart they're gonna be laying right there well beyond that with a .223 if you have the know how to make that happen. The flatter shooting cartridges like the 22-250 make hits easier at a distance because you can hold on fur at greater distances. If you can put that bullet in those places I mentioned above anyway. If not, you'll just have to walk further to try and find it and further to drag it if you do.
Regardless of how fast it's shooting, bullet weight or type of bullet you're going to have to shoot the coyote in the vitals. I don't care if you're shooting a .270, if a coyote is standing out there broadside at 200 yards you're not gonna shoot it in the ass or in the guts. It's gonna have disappointing results if you do. It's a good practice to shoot them where they'll die regardless of cartridge.
The 22-250 really shines when you're shooting coyotes at 300+ yards. And even at 300 yards I don't feel under gunned with the .223 by any means. If you hit coyotes in the head, neck, lungs or heart they're gonna be laying right there well beyond that with a .223 if you have the know how to make that happen. The flatter shooting cartridges like the 22-250 make hits easier at a distance because you can hold on fur at greater distances. If you can put that bullet in those places I mentioned above anyway. If not, you'll just have to walk further to try and find it and further to drag it if you do.
Regardless of how fast it's shooting, bullet weight or type of bullet you're going to have to shoot the coyote in the vitals. I don't care if you're shooting a .270, if a coyote is standing out there broadside at 200 yards you're not gonna shoot it in the ass or in the guts. It's gonna have disappointing results if you do. It's a good practice to shoot them where they'll die regardless of cartridge.
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