Uncle, I ran them for years. We used as long 14-12 Twist barrels as we could stand shooting 60g sierra's with H335 and would get 10K rounds on a barrel, IF the chamber reamer used had zero freebore. Today, the 55g Noslers I shoot in a 27" at 3850, and 65g V max at 3550, 70g tnt at 3500, all with AA2230 or H335 using only 7 1/2 primers.
When the wind comes up, it would help to have a 243, 6x47 Lapua, or 6 XC with .030 freebore and shoot the 87g V max with AA2700 or Win 760, which would help throat wear.