Powder charges from any source are just a reference for me.
Just from book to book, company to company the ranges are extreme. And for good reason!
Just the round count on your own particular rifle will affect velocity data. Probably one of the biggest things i have found affecting pressure is case capacity variations of different manufactures brass.
WLR primers will definitely increase pressure with certain powders as they are hotter primers. Expect +50fps
Many times just a different lot of the same powder can be different by 1-2 grains in larger cartridges!
I would say much of the time, I hit book velocity prior to reaching max load. (this is usually at, or very close to where i stop going up in charge weight)
Sometimes book max velocity is much lower. In this case i usually keep adding until velocity is adequate.
Powder charges are just a reference.
If you run your brass over pressure it will not respond to the sizing die like brass ran inside its pressure limits. This creates fliers.
It is best to do this right, (as AWS posted) Or just keep buying factory ammo.
I am starting to buy more and more of Hornady's factory ammo these days. This is from a guy who would not touch factory ammo ever!