We live in a technology crazed/dependent world. I'd imagine there are lots of "hunters" that have never called in a critter without an ecaller.
By far the biggest advantage to an ecaller is getting the sound away from you. Period. For a solo hunter that alone is a huge advantage. The sounds themselves run a distant second. When I use an ecaller I use maybe three sounds...that's it. There are times a hand call is the better option. Sneaking over a rise to call a valley on the other side, you can just sit, let things settle and start calling. No walking out, setting up the call and walking back, spreading around your scent. Then when finished walking back out to retrieve. Most of the time when there's two of us we still use hand calls most of the time.